Since 2010, the Institute for Mummy Studies hosts an ancient DNA (aDNA) facility dedicated to the molecular analysis of ancient human remains.
aDNA laboratory provides an excellent basis to carry out research at
the intersection between archaeology/anthropology and molecular biology.
The main focus of our studies is genomic and relationship analysis of
ancient human remains and the diagnosis of ancient pathogens to predict
disease onsets and developments. These studies are complemented by
histological investigations and we aim to constantly improve and develop
molecular methods adapted to ancient DNA research.
Description of the ancient DNA facility
Pre and Post PCR
ancient DNA facility is divided in two separate areas. Sample
processing, DNA extraction, library preparation for next generation
sequencing (NGS) and polymerase chain reaction (PCR) setup steps are
performed in a dedicated pre-PCR area following strict protocols
required for the study of ancient DNA. The working steps are carried out
in three different rooms.
The second area, the post-PCR area, is
used for all molecular downstream processes such as PCR and NGS as well
as histological analysis.
- I Gowning room
- II Sample processing room
- III DNA extraction room
- IV PCR- and reagent setup room
- V-VIII post-PCR rooms